| [1] |
Ophelders DRMG, Gussenhoven R, Klein L, et al. Preterm brain injury, antenatal triggers, and therapeutics: timing is key[J]. Cells, 2020, 9(8): 1871. DOI: 10.3390/cells9081871.
|
| [2] |
Guillot M, Miller SP. The dimensions of white matter injury in preterm neonates[J]. Semin Perinatol, 2021, 45(7): 151469. DOI: 10.1016/j.semperi.2021.151469.
|
| [3] |
Back SA. White matter injury in the preterm infant: pathology and mechanisms[J]. Acta Neuropathol, 2017, 134(3): 331-349. DOI: 10.1007/s00401-017-1718-6.
|
| [4] |
Romberg J, Wilke M, Allgaier C, et al. MRI-based brain volumes of preterm infants at term: a systematic review and Meta-analysis[J]. Arch Dis Child Fetal Neonatal Ed, 2022, 107(5): 520-526. DOI: 10.1136/archdischild-2021-322846.
|
| [5] |
Back SA, Luo NL, Borenstein NS, et al. Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury[J]. J Neurosci, 2001, 21(4): 1302-1312. DOI: 10.1523/JNEUROSCI.21-04-01302.2001.
|
| [6] |
Zhang Y, Banihashemi L, Versace A, et al. Associations among white matter microstructural changes and the development of emotional reactivity and regulation in infancy[J]. Mol Psychiatry, 2025, 30(7): 3168-3174. DOI: 10.1038/s41380-025-03025-w.
|
| [7] |
Simons M, Gibson EM, Nave KA. Oligodendrocytes: myelination, plasticity, and axonal support[J]. Cold Spring Harb Perspect Biol, 2024, 16(10): a041359. DOI: 10.1101/cshperspect.a041359.
|
| [8] |
Mishra SK, Tiwari SP. Bioenergetics of axon integrity and its regulation by oligodendrocytes and schwann cells[J]. Molecular Neurobiol, 2024, 61(8): 5928-5934. DOI: 10.1007/s12035-024-03950-x.
|
| [9] |
Xing J, Lukomska A, Rheaume BA, et al. Post-injury born oligodendrocytes incorporate into the glial scar and contribute to the inhibition of axon regeneration[J]. Development, 2023, 150(8): dev201311. DOI: 10.1242/dev.201311.
|
| [10] |
Jantzie LL, Corbett CJ, Berglass J, et al. Complex pattern of interaction between in uterohypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function[J]. J Neuroinflammation, 2014, 11: 131. DOI: 10.1186/1742-2094-11-131.
|
| [11] |
Gilles FH, Leviton A. Neonatal white matter damage and the fetal inflammatory response[J]. Semin Fetal Neonatal Med, 2020, 25(4): 101111. DOI: 10.1016/j.siny.2020.101111.
|
| [12] |
Brew N, Walker D, Wong FY. Cerebral vascular regulation and brain injury in preterm infants[J]. Am J Physiol Regul Integr Comp Physiol, 2014, 306(11): R773-R786. DOI: 10.1152/ajpregu.00487.2013.
|
| [13] |
Yao L, Peng P, Ding T, et al. m6A-induced lncRNA MEG3 promotes cerebral ischemia-reperfusion injury via modulating oxidative stress and mitochondrial dysfunction by hnRNPA1/Sirt2 axis[J]. Mol Neurobiol, 2024, 61(9): 6893-6908. DOI: 10.1007/s12035-024-04005-x.
|
| [14] |
Martini S, Castellini L, Parladori R, et al. Free radicals and neonatal brain injury: from underlying pathophysiology to antioxidant treatment perspectives[J]. Antioxidants (Basel), 2021, 10(12): 2012. DOI: 10.3390/antiox10122012.
|
| [15] |
Liu C, Ju R. Potential role of endoplasmic reticulum stress in modulating protein homeostasis in oligodendrocytes to improve white matter injury in preterm infants[J]. Mol Neurobiol, 2024, 61(8): 5295-5307. DOI: 10.1007/s12035-023-03905-8.
|
| [16] |
Pierre WC, Smith PLP, Londono I, et al. Neonatal microglia: the cornerstone of brain fate[J]. Brain Behav Immun, 2017, 59: 333-345. DOI: 10.1016/j.bbi.2016.08.018.
|
| [17] |
Woodburn SC, Bollinger JL, Wohleb ES. The semantics of microglia activation: neuroinflammation, homeostasis, and stress[J]. J Neuroinflammation, 2021, 18(1): 258. DOI: 10.1186/s12974-021-02309-6.
|
| [18] |
Fang M, Yu Q, Ou J, et al. The neuroprotective mechanisms of PPAR-γ:Inhibition of microglia-mediated neuroinflammation and oxidative stress in a neonatal mouse model of hypoxic-ischemic white matter injury[J]. CNS Neurosci Ther, 2024, 30(11): e70081. DOI: 10.1111/cns.70081.
|
| [19] |
Wang LW, Tu YF, Huang CC, et al. JNK signaling is the shared pathway linking neuroinflammation, blood-brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain[J]. J Neuroinflammation, 2012, 9: 175. DOI: 10.1186/1742-2094-9-175.
|
| [20] |
Zhang C, Qiu M, Fu H. Oligodendrocytes in central nervous system diseases: the effect of cytokine regulation[J]. Neural Regen Res, 2024, 19(10): 2132-2143. DOI: 10.4103/1673-5374.392854.
|
| [21] |
Schmitz T, Chew LJ. Cytokines and myelination in the central nervous system[J]. ScientificWorldJournal, 2008, 8: 1119-1147. DOI: 10.1100/tsw.2008.140.
|
| [22] |
Strunk T, Inder T, Wang X, et al. Infection-induced inflammation and cerebral injury in preterm infants[J]. Lancet Infect Dis, 2021, 21(6): e146-e158. DOI: 10.1016/S1473-3099(20)30738-1.
|
| [23] |
Haruwaka K, Ikegami A, Tachibana Y, et al. Dual microglia effects on blood brain barrier permeability induced by systemic inflammation[J]. Nat Commun, 2019, 10(1): 5816. DOI: 10.1038/s41467-019-13812-z.
|
| [24] |
Serdar M, Walther K A, Gallert M, et al. Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury[J]. J Neuroinflammation, 2025, 22(1): 57. DOI: 10.1186/s12974-025-03389-4.
|
| [25] |
Liu L, Fang L, Duan B, et al. Multi-hit white matter injury-induced cerebral palsy model established by perinatal lipopolysaccharide injection[J]. Front Pediatr, 2022, 10: 867410. DOI: 10.3389/fped.2022.867410.
|
| [26] |
Li L, Yang J, Liu T, et al. Role of the gut-microbiota-metabolite-brain axis in the pathogenesis of preterm brain injury[J]. Biomed Pharmacother, 2023, 165: 115243. DOI: 10.1016/j.biopha.2023.115243.
|
| [27] |
Fock E, Parnova R. Mechanisms of blood-brain barrier protection by microbiota-derived short-chain fatty acids[J]. Cells, 2023, 12(4): 657. DOI: 10.3390/cells12040657.
|
| [28] |
Vaes JEG, Brandt MJV, Wanders N, et al. The impact of trophic and immunomodulatory factors on oligodendrocyte maturation: potential treatments for encephalopathy of prematurity[J]. Glia, 2021, 69(6): 1311-1340. DOI: 10.1002/glia.23939.
|
| [29] |
Fang M, Lu L, Lou J, et al. FGF21 alleviates hypoxic-ischemic white matter injury in neonatal mice by mediating inflammation and oxidative stress through PPAR-γ signaling pathway[J]. Mol Neurobiol, 2024, 62(4): 4743-4768. DOI: 10.1007/s12035-024-04549-y.
|
| [30] |
Seitz M, Köster C, Dzietko M, et al. Hypothermia modulates myeloid cell polarization in neonatal hypoxic-ischemic brain injury[J]. J Neuroinflammation, 2021, 18(1): 266. DOI: 10.1186/s12974-021-02314-9.
|
| [31] |
Han Y, Li X, Li J, et al. Inosine treatment attenuates white matter injury in neonatal rats exposed to maternal inflammation[J]. Neurochem Res, 2025, 50(3): 176. DOI: 10.1007/s11064-025-04429-4.
|
| [32] |
Wolf HT, Huusom LD, Henriksen TB, et al. Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with Meta-analysis and trial sequential analysis[J]. BJOG, 2020, 127(10): 1180-1188. DOI: 10.1111/1471-0528.16238.
|
| [33] |
Song J, Wang Y, Xu F, et al. Erythropoietin improves poor outcomes in preterm infants with intraventricular hemorrhage[J]. CNS Drugs, 2021, 35(6): 681-690. DOI: 10.1007/s40263-021-00817-w.
|
| [34] |
Liu S, Zhang X, Liu Y, et al. Early application of caffeine improves white matter development in very preterm infants[J]. Respir Physiol Neurobiol, 2020, 281: 103495. DOI: 10.1016/j.resp.2020.103495.
|
| [35] |
Beghetti I, Barone M, Brigidi P, et al. Early-life gut microbiota and neurodevelopment in preterm infants: a narrative review[J]. Front Nutr, 2023, 10: 1241303. DOI: 10.3389/fnut.2023.1241303.
|
| [36] |
Drobyshevsky A, Synowiec S, Goussakov I, et al. Intestinal microbiota modulates neuroinflammatory response and brain injury after neonatal hypoxia-ischemia[J]. Gut Microbes, 2024, 16(1): 2333808. DOI: 10.1080/19490976.2024.2333808.
|
| [37] |
Vaes JEG, van Kammen CM, Trayford C, et al. Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity[J]. Glia, 2020, 69(3): 655-680. DOI: 10.1002/glia.23919.
|
| [38] |
Razak A, Zhou L, Jenkin G, et al. Cord blood-derived cell therapies for preterm brain injury[J]. Early Hum Dev, 2025, 210: 106369. DOI: 10.1016/j.earlhumdev.2025.106369.
|
| [39] |
Vaes JEG, Onstwedder SM, Trayford C, et al. Modifying the secretome of mesenchymal stem cells prolongs the regenerative treatment window for encephalopathy of prematurity[J]. Int J Mol Sci, 2024, 25(12): 6494. DOI: 10.3390/ijms25126494.
|
| [40] |
Wang S, Li C, Kang X, et al. Agomelatine promotes differentiation of oligodendrocyte precursor cells and preserves white matter integrity after cerebral ischemic stroke[J]. J Cereb Blood Flow Metab, 2024, 44(12): 1487-1500. DOI: 10.1177/0271678x241260100.
|
| [41] |
Xue H, Ding Z, Chen X, et al. Dexmedetomidine improves long-term neurological outcomes by promoting oligodendrocyte genesis and myelination in neonatal rats following hypoxic-ischemic brain injury[J]. Mol Neurobiol, 2024, 62(4): 4866-4880. DOI: 10.1007/s12035-024-04564-z.
|
| [42] |
Cui S hao, Suo N, Yang Y, et al. The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation[J]. Acta Pharmacol Sin, 2024, 45(3): 490-501. DOI: 10.1038/s41401-023-01183-7.
|