子宫肌瘤(UM)是女性生殖道最常见良性肿瘤，好发于育龄期，病因迄今尚未阐明，其发生、发展可能与雌、孕激素等相关。虽然孕期胎盘产生雌、孕激素水平随着孕龄增加而增加，但是UM体积，并非随着雌、孕激素水平升高而相应增大。孕期母体产生的其他内分泌激素及羊膜腔张力、子宫收缩等因素，同样也影响着UM血供及生长方式。妊娠合并UM是一些不良妊娠结局的高危因素，如可能导致早产、胎盘早剥、产后出血等，同时也可增加剖宫产术分娩率。因此，本文拟结合国内外相关文献对妊娠合并UM在孕期的变化，及其与不良妊娠结局的关系进行综述如下，旨在提高临床医师对妊娠合并UM的认识，为临床正确管理妊娠合并UM提供思路。

Uterine myoma (UM) is the most common benign tumor of the female genital tract, which often occurs in their reproductive age, the cause has not been clarified so far, and its occurrence and development may be related to estrogen and progesterone. Although the levels of estrogen and progesterone produced in the placenta during pregnancy increases with the increase of gestational age, but the volume of UM does not increase with the increase of estrogen and progesterone levels. Other endocrine hormones produced by the body during pregnancy, and amniotic cavity tension, uterine contraction and other factors also affect the blood supply and growth mode of uterine myoma. Pregnancy complicated with UM is a high risk factor for some adverse pregnancy outcomes, such as premature delivery, placental abruption, postpartum hemorrhage etc., and also increases the rate of cesarean delivery. Therefore, this article combines relevant literature at domestic and abroad to analyze the changes of UM during pregnancy and their association with adverse pregnancy outcomes, to improve the clinical understanding of pregnancy with UM and to provide ideas for clinical correct management of pregnancy with UM.