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中华妇幼临床医学杂志(电子版) ›› 2022, Vol. 18 ›› Issue (04) : 387 -392. doi: 10.3877/cma.j.issn.1673-5250.2022.04.003

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内脏利什曼病临床药物治疗研究现状
袁传杰, 杨雪, 朱渝()   
  1. 四川大学华西第二医院儿科、出生缺陷与相关妇儿疾病教育部重点实验室,成都 610041
  • 收稿日期:2021-12-01 修回日期:2022-05-09 出版日期:2022-08-01
  • 通信作者: 朱渝

Current research status of clinical pharmaceutical treatment options for visceral Leishmaniasis

Chuanjie Yuan, Xue Yang, Yu Zhu()   

  1. Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2021-12-01 Revised:2022-05-09 Published:2022-08-01
  • Corresponding author: Yu Zhu
  • Supported by:
    Project of Science & Technology Department of Sichuan Province(2022YFS0243)
引用本文:

袁传杰, 杨雪, 朱渝. 内脏利什曼病临床药物治疗研究现状[J]. 中华妇幼临床医学杂志(电子版), 2022, 18(04): 387-392.

Chuanjie Yuan, Xue Yang, Yu Zhu. Current research status of clinical pharmaceutical treatment options for visceral Leishmaniasis[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2022, 18(04): 387-392.

内脏利什曼病(VL)又被称为黑热病,是人体被利什曼原虫感染所致的播散性原虫病。VL患者的临床表现包括长期发热,肝、脾大,全血细胞减少及进行性贫血与消瘦等。我国治疗VL的临床药物以5价锑剂为主。目前临床治疗VL可供选择的药物种类少。笔者拟就VL患者药物治疗方案的最新研究进展进行阐述,旨在为该病患者的临床治疗提供参考。

Visceral Leishmaniasis (VL), also known as Kala-Azar, is a disseminated protozoal infection disease caused by Leishmania. Clinical manifestations of VL patients include chronic fever, hepatosplenomegaly, pancytopenia, progressive anemia and emaciation, etc.. In China, penta-valent antimony is the main treatment option for VL patients. At present, there are a few kinds of medicine available for clinical treatment of VL. This article focuses on review latest research progresses of clinical treatment for VL patients so as to provide reference for physicians.

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