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中华妇幼临床医学杂志(电子版) ›› 2015, Vol. 11 ›› Issue (4) : 530 -534. doi: 10.3877/cma.j.issn.1673-5250.2015.04.020

所属专题: 文献

综述

先天性膈疝的诊治进展
陈文科, 侯昉   
  1. 563003 遵义医学院
    610072 成都,四川省人民医院
  • 收稿日期:2015-01-19 修回日期:2015-06-19 出版日期:2015-08-01

Pathogenesis and clinical progress in diagnosis and treatment of congenital diaphragmatic hernia

Wenke Chen, Fang Hou   

  1. Zunyi Medical College, Zunyi 563003, Guizhou Province, China
    Department of Pediatric Surgery, Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China
  • Received:2015-01-19 Revised:2015-06-19 Published:2015-08-01
引用本文:

陈文科, 侯昉. 先天性膈疝的诊治进展[J/OL]. 中华妇幼临床医学杂志(电子版), 2015, 11(4): 530-534.

Wenke Chen, Fang Hou. Pathogenesis and clinical progress in diagnosis and treatment of congenital diaphragmatic hernia[J/OL]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2015, 11(4): 530-534.

先天性膈疝(CDH)是膈肌异常伴随肺发育不良(PH)、新生儿持续肺动脉高压(PPHN)等病理、生理改变的先天性疾病,其发病率、病死率均较高。迄今为止,CDH的具体病因、最佳治疗措施及预后影响因素均未阐明,这使得CDH的诊治具有挑战性。近年由于医学技术的不断进步、各种治疗措施的不断改进,CDH患儿的存活率有所提高。然而,CDH存活患儿的长期跟踪随访,尚需引起临床医师的足够重视,包括如何改善其预后、提高生活质量等。笔者拟就CDH的最新诊治进展,进行综述如下。

Congenital diaphragmatic hernia (CDH) is an uncommon congenital anomaly of the diaphragm with pulmonary hypoplasia (PH) and persistent pulmonary hypertension as serious consequences (PPHN). Till now, the etiopathogenisis and best treatment strategies are still largely unknown, and practice strategies vary widely among different centres, so CDH still remains a challenging condition. In recent years, with the development of medical technology and improvement of treatment, survival rates of CDH patients appear to have increased. Survivors have been shown to be at risk for many long-term morbidities, so the importance of long-term follow-up of CDH survivals should be highlighted, including long-term prognosis and quality of life. This research focuses on the progress research of current diagnosis and treatment of CDH.

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