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中华妇幼临床医学杂志(电子版) ›› 2010, Vol. 06 ›› Issue (04) : 300 -302. doi: 10.3877/cma.j.issn.1673-5250.2010.04.026

综述

抑制血管生成治疗子宫内膜异位症
关锦图, 陈云卿   
  1. 528000 广东佛山,佛山市第一人民医院妇科
  • 出版日期:2010-08-01

Antiangiogenesis Therapy for Endometriosis

Jin-tu GUAN, Yun-qing Chen   

  1. Department of Gynecology, First People's Hospital of Foshan, Foshan 528000, Guangdong Province, China
  • Published:2010-08-01
引用本文:

关锦图, 陈云卿. 抑制血管生成治疗子宫内膜异位症[J]. 中华妇幼临床医学杂志(电子版), 2010, 06(04): 300-302.

Jin-tu GUAN, Yun-qing Chen. Antiangiogenesis Therapy for Endometriosis[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2010, 06(04): 300-302.

子宫内膜异位症(endometriosis,EMS)发生发展的必要条件是新生血管形成。由于体内抑制因子活性降低,或某些血管生成因子活性增高,可致子宫内膜异位症患者血管过度生成,这成为促成子宫异位内膜种植和生长的最重要步骤。本文主要从血管促进因子在新血管生成中的作用及血管生成抑制剂对子宫内膜异位症的治疗作用两方面进行综述如下。

New blood vessel growth is a necessary condition for the development of endometriosis. Excessive blood vessel formation on endometriosis could caused the decreasement of in vivo inhibitor activity or the increasement of activity of certain angiogenic factors, which became the most important step during the cultivation and growth of ectopic endometrium. This article focused on the following two points, the significance of vascular promoting factor during the growth of new blood vessel, and angiogenesis inhibitors on the treatment of endometriosis.

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