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中华妇幼临床医学杂志(电子版) ›› 2010, Vol. 06 ›› Issue (01) : 22 -24. doi: 10.3877/cma.j.issn.1673-5250.2010.01.107

论著

超声检查在新生儿阻塞性肝炎与先天性胆道闭锁鉴别诊断中的应用价值
苏英姿, 袁新宇, 张玉林, 李龙   
  1. 100020 北京,首都儿科研究所附属儿童医院超声科
    100020 北京,首都儿科研究所附属儿童医院放射科
    100020 北京,首都儿科研究所附属儿童医院外科
  • 出版日期:2010-02-01

Value of Ultrasound Study on Differential Diagnosis of Neonatal Obstructive Hepatitis and Congenital Biliary Atresia

Ying-zi SU, Xin-yu YUAN, Yu-lin ZHANG, Long LI   

  1. Capital Institute of Pediatrics, Beijing 100020, China
  • Published:2010-02-01
引用本文:

苏英姿, 袁新宇, 张玉林, 李龙. 超声检查在新生儿阻塞性肝炎与先天性胆道闭锁鉴别诊断中的应用价值[J/OL]. 中华妇幼临床医学杂志(电子版), 2010, 06(01): 22-24.

Ying-zi SU, Xin-yu YUAN, Yu-lin ZHANG, Long LI. Value of Ultrasound Study on Differential Diagnosis of Neonatal Obstructive Hepatitis and Congenital Biliary Atresia[J/OL]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2010, 06(01): 22-24.

目的

通过回顾性对比和分析新生儿阻塞性肝炎(neonatal obstructive hepatitis)和先天性胆道闭锁(congenital biliary atresia)患儿的超声学检查结果,探讨超声检查在两种疾病鉴别诊断中的应用价值。

方法

2005年6月至2008年10月,对本院19例经腹腔镜胆道X射线造影证实为重症新生儿阻塞性肝炎和21例经病理学检查证实为先天性胆道闭锁患儿空腹时超声图像中胆囊形态和大小,进食前、后胆囊收缩程度及有无肝门纤维块等进行回顾性统计和分析。

结果

超声检查时,两组患儿空腹胆囊的形态异常率及胆囊长轴缩短率比较,先天性胆道闭锁组高于阻塞性肝炎组,且差异有显著意义(P<0.05);肝门纤维块出现率比较,差异亦有显著意义(P=0.001)。两组患儿进食后,胆囊收缩功能明显消失率比较,差异有显著意义(P=0.028)。

结论

早期行超声检查,通过观察患儿空腹时胆囊长轴长度和形态及有无肝门纤维块,将有助于两种病变的鉴别诊断。进食后胆囊收缩功能明显消失,对两种疾病的鉴别诊断有协助诊断意义。

Objective

To evaluate the value of ultrasound in differential diagnosis of neonatal obstructive hepatitis and congenital biliary atresia.

Methods

From June 2005 to October 2008, ultrasound data of 19 cases with neonatal obstructive hepatitis and 21 cases with congenital biliary atresia were reviewed retrospectively. The gall bladder shape and size, gall bladder contraction and the visualization of the triangular cord sign were analyzed.

Results

Statistically, the gall bladder size of patients with neonatal obstructive hepatitis was significantly greater than that of patients with congenital biliary atresia(P=0.001). The presenting rates of gall bladder contraction and the triangular cord sign of two groups were significantly different(P=0.028).

Conclusion

The size and shape of gall bladder, triangular cord sign, and the ability of gall bladder contraction were useful sonographically in differential diagnosis between neonatal obstructive hepatitis and congenital biliary atresia.

图1 先天性胆道闭锁(超声显示,胆囊空瘪,囊壁呈皱缩状)
图2 先天性胆道闭锁(超声显示,左、右门静脉分叉处出现条索状高回声区。三角带征)
1 李正,王慧贞,吉士俊.实用小儿外科学[M].北京:人民卫生出版社,2001, 1046-1060.[Li Z, Wang HZ, Ji SJ. Practical pediatric surgery[M]. Beijing: People's Medical Publishing House, 2001, 1046-1060.]
2 Gubernick JA, Rosenberg HK, Ilaslan H, et al. US approach to jaundice in infants and children[J]. Radiographics, 2000, 20(1): 173-195.
3 Zheng YS, Zhang LD, Zhou Q, et al. B-ultrasound studies of biliary atresia and neonatal hepatitis in infants[J]. Chin J Pediatr Surg, 1991, 12: 357-358.[郑毓珊,张鲁东,周琪,等. B超检测在胆道闭锁和新生儿肝炎鉴别诊断中的应用[J].中华小儿外科杂志,1991, 12: 357-358.]
4 Kanegawa K, Akasaka Y, Kitamura E, et al. Sonographic diagnosis of biliary atresia in pediatric patients using the "triangular cord" sign versus gallbladder length and contraction[J]. AJR, 2003, 181(5): 1387-1390.
5 Choi SO, Park WH, Lee HJ, et al. "Triangular cord" :A sonographic finding applicable in the diagnosis of biliary atresia[J]. J Pediatr Surg, 1996, 31(3): 363-366.
6 Akram-Abdel MD, Magdy AF, Mona AK, et al. Diagnostic evaluation of cholestasis in infants and young children in Alexandria[J]. Int J Pediat Neonatol, 2006, 6: 1-13.
7 Liu JC. Differential diagnosis of obstructive jaundice in infants[J]. J Appl Clin Pediatr, 2003, 18(7): 506-508.[刘钧澄.婴儿阻塞性黄疸的鉴别诊断[J].实用儿科临床杂志,2003, 18(7): 506-508.]
8 Farrant P, Meire HB, Mieli-Vergani G. Improved diagnosis of extraheptic biliary atresia by high frequency ultrasound of the gall bladder[J]. Br J Radiol, 2001, 74(886): 952-954.
9 Farrant P, Meire HB, Mieli-Vergani G. Ultrasound features of the gall bladder in infants presenting with conjugated hyperbilirubinaemia[J]. Br J Radiol, 2000, 73(875): 1154-1158.
10 Chardot C. Biliary atresia[J]. Orphanet J Rare Dis, 2006, 1: 28.
11 Lee HJ, Lee SM, Park WH, et al. Objective criteria of triangular cord sign in biliary atresia on US scans[J]. Radiology,2003, 229(2): 395-400.
12 Ohi R. Biliary atresia[M]. //Balistreri WF, Ohi R, Todani T, et al, ed. Hepatobiliary pancreatic and splenic disease in children. Amsterdam: Elsevier, 1997, 231-260.
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