观察间苯三酚对促进产程进展的作用效果及血浆皮质醇、血糖与胰岛素比值变化。

选择正常足月单胎孕妇55例，将其分为间苯三酚组(26例)及正常对照组(29例)，观察两组孕妇产程变化、胎儿情况及产妇血浆皮质醇、血糖与胰岛素比值。

①活跃期：间苯三酚组为(86. 23±45. 86)min，对照组为(172. 86±144. 32)min，两组比较，差异有显著意义(P<0. 05)。②第二产程：间苯三酚组为(63. 12±29.47)min，对照组为(86.170±30.27)min，两组比较，差异有显著意义(P<0. 05)。③两组间，血浆皮质醇、血糖与胰岛素比值、产后出血量、胎心变化及新生儿Apgar评分比较，差异无显著意义。

间苯三酚可安全、有效地加速产程进展，对产妇正常应激反应无明显影响。该药为临床加速产程进展提供了一种更佳治疗选择。

The current study was designed to observe the effects of phloroglucinol on child birth process, plasma cortisol and ratio of glucose/insulin.

Fifty-five primiparae were randomly divided into two groups, phloroglucinol group(n= 26) and control group (n= 29). The labor time, fetal distress and postpartum hemorrhage condition between the two groups were evaluated, meanwhile diversity of plasma cortisol and ratio of glucose/insulin were also observed.

① The mean time of full dilation of cervix was 86. 23 ± 45. 85 min in study group, and 172. 86 ± 144. 32 min was found in control group (P<0. 05).② Comparing to 86. 17 ± 30. 27 minutes during second stage of control group, only 63. 12±29. 47 min was needed to finish second stage in phloroglucinol group (P<0. 05).③ There are no significant difference in the fetal suffocation, weight of newborns and degree of postpartum hemorrhage between the two groups, meanwhile no obvious difference between two groups in plasma cortisol and ratio of glucose/insulin were observed.

Phloroglucinol can effectively improve cervical dilation and decrease labor time, has no adverse effect to puerperas and fetus. Phloroglucinol has no effect on normal stress reaction of puerperas.