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中华妇幼临床医学杂志(电子版) ›› 2017, Vol. 13 ›› Issue (05) : 616 -620. doi: 10.3877/cma.j.issn.1673-5250.2017.05.021

所属专题: 文献

综述

子痫前期与全身炎症反应关系的研究进展
赵舒1, 严滨2,()   
  1. 1. 116000 大连医科大学附属第一医院;550002 贵阳,贵州省人民医院
    2. 116000 大连医科大学附属第一医院
  • 收稿日期:2017-04-11 修回日期:2017-08-09 出版日期:2017-10-01
  • 通信作者: 严滨

Relationship between preeclampsia and systemic inflammatory response: research progress

Shu Zhao1, Bin Yan2,()   

  1. 1. First Hospital Affiliated to Dalian Medical University, Dalian 116000, Liaoning Province, China;Guizhou Province People′s Hospital, Guiyang 550002, Guizhou Province, China
    2. First Hospital Affiliated to Dalian Medical University, Dalian 116000, Liaoning Province, China
  • Received:2017-04-11 Revised:2017-08-09 Published:2017-10-01
  • Corresponding author: Bin Yan
  • About author:
    Corresponding author: Yan Bin, Email:
引用本文:

赵舒, 严滨. 子痫前期与全身炎症反应关系的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2017, 13(05): 616-620.

Shu Zhao, Bin Yan. Relationship between preeclampsia and systemic inflammatory response: research progress[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2017, 13(05): 616-620.

子痫前期(PE)是一种以孕龄为20孕周后出现的以高血压、蛋白尿及水肿为主要临床表现的综合征,是妊娠期特有的疾病,严重危及母儿生命。胎盘是PE发病的前提,分娩是缓解PE最好的方式,而寻找最佳分娩时机是关键。近年较多的研究探讨可以更好的反应PE的生物标志物,旨在指导PE的诊治。研究结果证实,全身炎症反应是PE发病的主要病因,笔者拟就对PE与全身炎症反应的关系进行综述。

Preeclampsia(PE) is defined as a clinical manifestation which is characterized by new onset hypertension and proteinuria after 20 gestational weeks. PE is an important factor of maternal morbidity and mortality as well as perinatal morbidity and mortality. The placenta is the prerequisite for the development of PE; and hereby, the delivery is the best final treatment of PE. So the proper timing of the delivery is crucial. A lot of researches aimed at seeking better biomarkers of PE, which can be used to guide the diagnosis and treatment of PE. At present, a lot of researches suggest that systemic transitional inflammation is main cause of PE. This article reviewes related indexes associated with systemic inflammatory response in PE.

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