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中华妇幼临床医学杂志(电子版) ›› 2017, Vol. 13 ›› Issue (02) : 226 -230. doi: 10.3877/cma.j.issn.1673-5250.2017.02.020

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综述

卵巢癌肿瘤干细胞及其标志物在卵巢癌诊疗中作用的研究进展
敬宏1, 牛晓宇2,()   
  1. 1. 643000 自贡,四川卫生康复职业学院护理系;610041 成都,四川大学华西第二医院妇产科、出生缺陷与相关妇儿疾病教育部重点实验室
    2. 610041 成都,四川大学华西第二医院妇产科、出生缺陷与相关妇儿疾病教育部重点实验室
  • 收稿日期:2016-12-12 修回日期:2017-02-27 出版日期:2017-04-01
  • 通信作者: 牛晓宇

Roles of ovarian cancer stem cell and its markers in diagnosis and treatment of ovarian cancer: research progress

Hong Jing1, Xiaoyu Niu2,()   

  1. 1. Department of Nursing, Sichuan Vocational College of Health and Rehabilitation, Zigong 643000, Sichuan Province, China; Department of Gynaecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    2. Department of Gynaecology and Obstetrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2016-12-12 Revised:2017-02-27 Published:2017-04-01
  • Corresponding author: Xiaoyu Niu
  • About author:
    Corresponding author: Niu Xiaoyu, Email:
引用本文:

敬宏, 牛晓宇. 卵巢癌肿瘤干细胞及其标志物在卵巢癌诊疗中作用的研究进展[J/OL]. 中华妇幼临床医学杂志(电子版), 2017, 13(02): 226-230.

Hong Jing, Xiaoyu Niu. Roles of ovarian cancer stem cell and its markers in diagnosis and treatment of ovarian cancer: research progress[J/OL]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2017, 13(02): 226-230.

卵巢癌是女性生殖系统常见的恶性肿瘤,所导致的患者死亡率居妇科肿瘤的首位。随着对卵巢癌研究的深入,已有越来越多的证据表明卵巢癌应纳入干细胞疾病之列。卵巢癌的早期诊断及早期治疗有赖于更多的卵巢癌干细胞标志物的发现和识别。笔者拟就目前国内外对卵巢癌干细胞的研究,从肿瘤干细胞(CSC)理论起源及其演变、卵巢癌干细胞的发现、卵巢癌干细胞与卵巢癌的关系及其分离纯化、卵巢癌干细胞标志物在卵巢癌早期诊断及治疗中的作用研究进展进行综述。

Ovarian cancer is one of the common malignant tumors, the mortality of ovarian cancer ranks first in gynecologic oncology. More and more researches suggest that ovarian cancer should be classified as stem cell diseases. The early diagnosis and early treatment of ovarian cancer depend on the detection and recognition of more ovarian neoplasm stem cell markers. In this review, we will make a review from the aspects of cancer stem cell (CSC) theory origin and its evolution, the discovery of ovarian neoplasms stem cells, ovarian neoplasms stem cells and the relationship between the ovarian neoplasms and its purification, ovarian neoplasms stem cell markers in the early diagnosis and treatment of ovarian cancer, and so on.

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