切换至 "中华医学电子期刊资源库"

中华妇幼临床医学杂志(电子版) ›› 2013, Vol. 09 ›› Issue (01) : 113 -116. doi: 10.3877/cma.j.issn.1673-5250.2013.01.031

所属专题: 文献

综述

早发型子痫前期病因及其预测的研究进展
冯亚玲1,*,*(), 许倩1, 项静英1   
  1. 1. 214002 江苏无锡,南京医科大学附属无锡妇幼保健院产科
  • 收稿日期:2012-10-08 修回日期:2013-01-05 出版日期:2013-02-01
  • 通信作者: 冯亚玲

Progress Research of Etiopathogenisis and Prediction of Early-Onset Pre-Eclampsia

Ya-ling FENG1(), Qian XU1, Jing-ying XIANG1   

  1. 1. Department of Obstetrics, Wuxi Matemal and Child Health Hospital Affiliated to Nanjing Medical University, Wuxi 214002, Jiangsu Province, China
  • Received:2012-10-08 Revised:2013-01-05 Published:2013-02-01
  • Corresponding author: Ya-ling FENG
  • About author:
    Corresponding author: FENG Ya-ling, Email:
引用本文:

冯亚玲, 许倩, 项静英. 早发型子痫前期病因及其预测的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2013, 09(01): 113-116.

Ya-ling FENG, Qian XU, Jing-ying XIANG. Progress Research of Etiopathogenisis and Prediction of Early-Onset Pre-Eclampsia[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2013, 09(01): 113-116.

早发型子痫前期的发病机制可能与易感基因及其多态性、胎盘源性细胞因子、免疫耐受异常等有关。早发型子痫前期的预测可从病史、外周血检测相关因子和彩色多普勒超声检查等多条途径进行。笔者拟就早发型子痫前期的病因及预测研究进展,进行综述如下。

Etiopathogenisis of early-onset pre-eclampsia involves predisposing genes polymorphism, placental coytokine dysfunction and immunological disorder. The patitent history, maternal peripheral blood correlation protein detection and color Doppler flow imaging (CDFI) may contribute to predict early-onset pre-eclampsia. This paper discusses the progress of recent studies in early-onset pre-eclampsia.

[1]
Vaisbuch E, Romero R, Mazak-iTovi S, et al. Retinol binding protein 4-a novel association with early-onset preeclampsia[J]. J Perinat Med, 2010, 38:129-139.
[2]
Ma RQ, Sun MN, Yang Z. Effects of preeclampsia-like symptoms at early gestational stage on feto-placental outcomes in a mouse model[J]. Chin Med J (Eng), 2010, 123:707-712.
[3]
Yang Z, Wang JL, Huang P, et al. Study on unparalleled damage of end organs in severe preeclampsia and perinatal outcomes[J]. Chin J Perinat Med, 2006, 91:10-14.
[4]
Jenkins SM, Head BB, Hauth JC. Severe preeclampsia at <25 weeks of gestation: Maternal and neonatal outcomes[J]. Am J Obstet Gynecol, 2002, 186(4):790-795.
[5]
Hall DR, Odendaal HJ, Steyn DW, et al. Expectant management of early onset severe preeclampsia: Maternal outcome[J]. BJOG, 2000, 107(10):1252-1257.
[6]
Chesley L, Copper DW. Genetics of hypertension in pregnancy: Possible single gene control of pre-eclampsia and eclampsia in the descendants of eclamptic women[J]. Br J Obstet Gynecol, 1986, 93:898-908.
[7]
Esplin MS, Fausett MB, Fraser A, et al. Paternal and maternal components of the predisposition to pre-eclampsia[J]. N Engl J Med, 2001, 344:867-876.
[8]
Haddad T. Update on pre-eclampsia[J]. Int Anesthesiol Clin, 2002, 40:115-135.
[9]
Junus K, Centlow M, Wikstrom AK, et al. Gene expression profiling of placentae from women with early- and late-onset pre-eclampsia: Down-regulation of the angiogenesis-related genes ACVRL1 and EGFL7 in early-onset disease[J]. Mol Hum Reprod, 2012, 18(3):146-155.
[10]
Lee T, Sumpio BE. Cell signalling in vascular cells exposed to cyclic strain: The emerging role of protein phosphatases[J]. Biotechnol Applochen, 2004, 39(pt2):129-139.
[11]
Aubard Y, Darodes N, Cantaloube M. Hyperhomocysteinemia and pregnancy review of our present understanding and therapeutic implications[J]. Eur J Obstet Gynecol Reprod Biol, 2000, 93(2):157-158.
[12]
Kanayama N. Trophoblastic injury: New etiological and pathological concept of preeclampsia[J]. Croat Med J, 2003, 44(2):148-156.
[13]
Chafet Z, Kuhnreich I, Sammar M, et al. First-trimester placental protein 13 screening for preeclampsia and intrauterine grow threstriction[J]. Am J Obstet Gynecol, 2007, 197(1):35, e1-7.
[14]
Sekizawa A, Sekizawa A, Purwosunu Y, et al. PP13 mRNA expression intropho-blasts from preeclamptic placentas[J]. Reprod Sci, 2009, 16(4):408-413.
[15]
Knox PG, Milner AE, Green NG, et al. Inhibition of metalloprotenase cleavage enhances the cytotoxicity of Fas Ligand[J]. J Immunol, 2003, 170(2):677-685.
[16]
Jongbloet PH. Offspring sex ratio at population level versus early and late onset preeclampsia[J]. Early Hum Dev, 2004, 79(2):159-163.
[17]
Shenhav S, Gemer O, Sassoon E, et al. Mid-trimester tripletest levels in early and late onset severe pre-eclampsia[J]. Prenat Diagn, 2002, 22(7):579-582.
[18]
Qi HB. Prediction of preeclampsia[J]. Chin J Obstet Gynecol Pediatr: Electron Ed, 2011, 7(3):194-196.
[19]
Nanjundan P, Bagga R, Kalra JK, et al. Risk factors for early onset severe pre-eclampsia and eclampsia among north Indian women[J]. Obstet Gynaecol, 2011, 31(5):384-389.
[20]
Cruz-Martinez R, Figueras F. The role of Doppler and placental screening[J]. Best Pract Res Clin Obstet Gynaecol, 2009, 23(6):845-855.
[21]
Baumann MU, Bersinger NA, Mohaupt MG, et al. First-trimester serum levels of soluble endoglin and soluble fms-like tyrosine kinase-1 as first-trimester markers for late-onset preeclampsia[J]. Am J Obstet Gynecol, 2008, 199(3):266. e1-6.
[22]
Kusanovic JP, Romero R, Chaiworapongsa T, et al. A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia[J]. J Matern Fetal Neonatal Med, 2009, 22(11):1021-1038.
[23]
Masoura S, Kalogiannidis IA, Gitas G, et al. Biomarkers in pre-eclampsia: A novel approach to early detection of the disease[J]. J Obstet Gynaecol, 2012, 32(7):609-616.
[24]
Vandenberghe G, Mensink I, Twisk JW, et al. First trimester screening for intra-uterine growth restriction and early-onset pre-eclampsia[J]. Prenat Diagn, 2011, 31(10):955-961.
[25]
Chafetz I, Kuhnreich I, Sammar M, et al. First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction[J]. Am J Obstet Gynecol, 2007, 197(1):35. e1-7.
[26]
Romero R, Kusanovic JP, Than NG, et al. First-trimester maternal serum PP13 in the risk assessment for preeclampsia[J]. Am J Obstet Gynecol, 2008, 199(2):122.e1-122.e11.
[27]
Akolekar R, Syngelaki A, Beta J, et al. Maternal serum placental protein 13 at 11- 13 weeks of gestation in preeclampsia[J]. Prenat Diagn, 2009, 29(12):1103-1108.
[28]
Cowans NJ, Spencer K, Meiri H. First-trimester maternal placental protein 13 levels in pregnancies resulting in adverse outcomes[J]. Prenat Diagn, 2008, 28(2):121-125.
[1] 范帅华, 郭伟, 郭军. 基于机器学习的决策树算法在血流感染预后预测中应用现状及展望[J]. 中华实验和临床感染病杂志(电子版), 2023, 17(05): 289-293.
[2] 李圣鹏, 方爱蓝, 刘诗宁, 王丹, 刘湘奇. 下颌阻生第三磨牙拔除难度的预测因素与评估方法[J]. 中华口腔医学研究杂志(电子版), 2023, 17(06): 441-445.
[3] 张俊, 罗再, 段茗玉, 裘正军, 黄陈. 胃癌预后预测模型的研究进展[J]. 中华普通外科学文献(电子版), 2023, 17(06): 456-461.
[4] 唐旭, 韩冰, 刘威, 陈茹星. 结直肠癌根治术后隐匿性肝转移危险因素分析及预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 16-20.
[5] 贾成朋, 王代宏, 陈华, 孙备. 可切除性胰腺癌预后术前预测模型的建立及应用[J]. 中华普外科手术学杂志(电子版), 2023, 17(05): 566-570.
[6] 邢晓伟, 刘雨辰, 赵冰, 王明刚. 基于术前腹部CT的卷积神经网络对腹壁切口疝术后复发预测价值[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 677-681.
[7] 顾睿祈, 方洪生, 蔡国响. 循环肿瘤DNA检测在结直肠癌诊治中的应用与进展[J]. 中华结直肠疾病电子杂志, 2023, 12(06): 453-459.
[8] 杨静, 顾红叶, 赵莹莹, 孙梦霞, 查园园, 王琪. 老年血液透析患者短期死亡的影响因素及列线图预测模型的预测作用[J]. 中华肾病研究电子杂志, 2023, 12(05): 254-259.
[9] 李飞翔, 段虎斌, 李晋虎, 吴昊, 王永红, 范益民. 急性颅脑损伤继发下肢静脉血栓的相关危险因素分析及预测模型构建[J]. 中华神经创伤外科电子杂志, 2023, 09(05): 277-282.
[10] 李海马, 孙恺, 刘如恩. 颅内单纯生殖细胞瘤患者的生存预测:基于SEER数据库的临床研究[J]. 中华神经创伤外科电子杂志, 2023, 09(05): 283-288.
[11] 王小娜, 谭微, 李悦, 姜文艳. 预测性护理对结直肠癌根治术患者围手术期生活质量、情绪及并发症的影响[J]. 中华消化病与影像杂志(电子版), 2023, 13(06): 525-529.
[12] 秦维, 王丹, 孙玉, 霍玉玲, 祝素平, 郑艳丽, 薛瑞. 血清层粘连蛋白、Ⅳ型胶原蛋白对代偿期肝硬化食管胃静脉曲张出血的预测价值[J]. 中华消化病与影像杂志(电子版), 2023, 13(06): 447-451.
[13] 张郁妍, 胡滨, 张伟红, 徐楣, 朱慧, 羊馨玥, 刘海玲. 妊娠中期心血管超声参数与肝功能的相关性及对不良妊娠结局的预测价值[J]. 中华消化病与影像杂志(电子版), 2023, 13(06): 499-504.
[14] 王亚丹, 吴静, 黄博洋, 王苗苗, 郭春梅, 宿慧, 王沧海, 王静, 丁鹏鹏, 刘红. 白光内镜下结直肠肿瘤性质预测模型的构建与验证[J]. 中华临床医师杂志(电子版), 2023, 17(06): 655-661.
[15] 程培丽, 李霞, 王亚丽. 孤立性脑桥梗死合并吞咽障碍的临床影响因素分析[J]. 中华脑血管病杂志(电子版), 2023, 17(05): 440-444.
阅读次数
全文


摘要