分析二级甲等医院妇产科围手术期患者的临床特征及抗菌药物的使用情况。

采用随机数字表法，通过医院信息系统随机选择2010年6月至2011年6月于沈阳市某二级甲等医院住院治疗的300例妇产科围手术期患者的病历资料为研究对象，对其临床特征进行调查、分析(本研究遵循的程序符合沈阳市苏家屯区中心医院人体试验委员会所制定的伦理学标准，得到该委员会批准，并与研究对象签署临床研究知情同意书)。

本组患者平均年龄为(43.5±10.7)岁，平均住院时间为(19.6±8.5)d，平均手术持续时间为(57.3±20.7)min。接受剖宫产术患者为109例(36.33%)，术后2次测量体温(T)>38℃为15例(5.0%)。抗菌药物应用率为100.0%(300/300)，头孢菌素类药物应用率为83.3%(250/300)。行病原体送检及药物敏感试验患者为5例(1.7%)。

本研究为完善二级甲等医院妇产科围手术期患者临床特征提供基础数据，初步提示该院抗菌药物应用存在不合理现象，为进一步探讨该院妇产科围手术期患者抗菌药物应用的合理性提供评价依据。

To analysis the clinical features and antibacterial drugs usage in patients with preoperative gynecological and obstetrical surgery from a second-grade class-A hospital.

From June 2010 to 2011, 300 patients with preoperative gynecological and obstetrical surgery were randomly selected in the study from a second-grade class-A hospital in Shenyang. The data of clinical features was analyzed retrospectively. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Sujiatun Central Hospital.Informed consent was obtained from each patients.

The average age, hospital stay and the average operation duration of 300 patients was (43.5±10.7) years old, (19.6±8.5) d and (57.3±20.7)min, respectively. There were 109 patients(36.33%) who accepted cesarean section, and 15 patients had fever(postoperative measurement, twice). The application rate of antibacterial drugs was 100.0%, and the application rate of cefoxitin was 41.33%. There were only 5 patients who accepted drug sensitivity test.

Management of antibacterial drugs administration for patients underwent gynecological and obstetrical surgery should be strengthened in this second-grade class-A hospital.