切换至 "中华医学电子期刊资源库"

中华妇幼临床医学杂志(电子版) ›› 2012, Vol. 08 ›› Issue (05) : 557 -560. doi: 10.3877/cma.j.issn.1673-5250.2012.05.001

所属专题: 文献

专家约稿

幼年型粒单核细胞白血病诊治进展
高举1,*(), 刘晓丽2   
  1. 1. 610041 成都,四川大学华西第二医院儿童血液肿瘤科
    2. 西藏民族学院医学院
  • 收稿日期:2012-07-30 修回日期:2012-09-06 出版日期:2012-10-01
  • 通信作者: 高举
  • 基金资助:
    自然科学基金面上项目资助(30973237); 卫生部属(管)2010-2012年度临床学科项目-子课题(128)
  • Received:2012-07-30 Revised:2012-09-06 Published:2012-10-01
引用本文:

高举, 刘晓丽. 幼年型粒单核细胞白血病诊治进展[J]. 中华妇幼临床医学杂志(电子版), 2012, 08(05): 557-560.

表1 JMML初诊时常见临床表现发生率(%)
Table 1 Incidence of clinical manifestations commonly seen in patients with JMML (%)
表2 国际JMML工作小组和EWOG-MDS制定的JMML诊断标准
Table 2 Diagnostic criteria of JMML by International JMML Working Group and EWOG-MDS
表3 国际JMML工作小组的JMML修订诊断标准
Table 3 Diagnostic criteria of JMML by International JMML Working Group
[1]
Arico M, Biondi A, Pui CH. Juvenile myelomonocytic leukemia[J]. Blood, 1997, 90(2):479-488.
[2]
Swerdlow SH, Campo E, Harris NL, et al. WHO classification of tumours of haematopoietic and lymphoid tissues[M]. Lyon, France:IARC, 2008.
[3]
Loh ML. Recent advances in the pathogenesis and treatment of juvenile myelomonocytic leukaemia[J]. Br J Hematol, 2011, 152(6):677-687.
[4]
Passmore SJ, Chessells JM, Kempski H. et al. Pediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia in the UK:A population-based study of incidence and survival[J]. Br J Haematol, 2003, 121(5):758-767.
[5]
Niemeyer CM, Arico M, Basso G, et al. Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases[J]. Blood, 1997, 89(10):3534-3543.
[6]
Liu XL, Wan Z, Wu JR, et al. The clinical diagnosis of JMML[J/CD]. Chin J Obstet Gynecol Pediatr:Electron Ed, 2012, 8(3):332-334.
[7]
Yoshimi A, Kojima S, Hirano N. Juvenile myelomonocytic leukemia epidemiology, etiopathogenesis, diagnosis, and management considerations[J]. Pediatr Drugs, 2010, 12 (1):11-21.
[8]
Sasaki H, Manabe A, Kojima S, et al. Myelodysplastic syndrome in childhood: A retrospective study of 189 patients in Japan[J]. Leukemia, 2001, 15(11):1713-1720.
[9]
Pylayeva-Gupta Y, Grabocka E, Bar-Sagi D. RAS oncogenes: Weaving a tumorigenic web[J]. Nat Rev Cancer, 2011, 11(11):761-774.
[10]
Tartaglia M, Niemeyer CM, Fragale A, et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia[J]. Nat Genet, 2003, 34 (2):148-150.
[11]
Chan RJ, Feng GS. PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase[J]. Blood, 2007, 109 (3):862-867.
[12]
Hof P, Pluskey S, Dhe-Paganon S, et al. Crystal structure of the tyrosine phosphatase SHP-2[J]. Cell, 1998, 92 (4):441-450.
[13]
Side LE, Emanuel PD, Taylor B, et al. Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1[J]. Blood, 1998, 92 (1):267-272.
[14]
Muramatsu H, Makishima H, Jankowska AM, et al. Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia[J]. Blood, 2010, 115(10):1969-1975.
[15]
Pasmant E, Ballerini P, Lapillonne H, et al. SPRED1 disorder and predisposition to leukemia in children[J]. Blood, 2009, 114(5):1131.
[16]
Aucagne R, Droin N, Paggetti J, et al. Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia[J]. J Clin Invest, 2011, 121(6):2361-2370.
[17]
Zenker M. Clinical manifestations of mutations in RAS and related intracellular signal transduction factors[J]. Curr Opin Pediatr, 2010, 23(4):443-451.
[18]
Tidyman WE, Rauen KA. The RASopathies: Developmental syndromes of Ras/MAPK pathway dysregulation[J]. Curr Opin Genet Dev, 2009, 19(3):230-236.
[19]
Emanuel PD. Juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia[J]. Leukemia, 2008, 22(7):1335-1342.
[20]
Chan RJ, Cooper T, Kratz CP, et al. Juvenile myelomonocytic leukemia: A report from the 2nd International JMML Symposium[J]. Leuk Res, 2009, 33(3):355-362.
[21]
Steelman LS, Franklin RA, Abrams SL, et al. Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy[J]. Leukemia, 2011, 25(7):1080-1094.
No related articles found!
阅读次数
全文


摘要