切换至 "中华医学电子期刊资源库"

中华妇幼临床医学杂志(电子版) ›› 2011, Vol. 07 ›› Issue (03) : 257 -260. doi: 10.3877/cma.j.issn.1673-5250.2011.03.021

综述

18F-氟代脱氧葡萄糖PET/CT在宫颈癌诊断与治疗的研究进展
马金平   
  1. 518020 广东深圳,暨南大学医学院附属二院
  • 出版日期:2011-06-01

Research Progress of 18F-FDG PET/CT in the Diagnosis and Treatment of Cervical Cancer

Jin-ping MA   

  1. Department of Obstetrics and Gynecology, Shenzhen People's Hospital, Shenzhen 518020, Guangdong Province, China
  • Published:2011-06-01
  • Supported by:
    * Project No. 2008BA157B03, supported by the National Science & Technology Pillar Program in the Eleventh Five-year Plan Period
引用本文:

马金平. 18F-氟代脱氧葡萄糖PET/CT在宫颈癌诊断与治疗的研究进展[J/OL]. 中华妇幼临床医学杂志(电子版), 2011, 07(03): 257-260.

Jin-ping MA. Research Progress of 18F-FDG PET/CT in the Diagnosis and Treatment of Cervical Cancer[J/OL]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2011, 07(03): 257-260.

宫颈癌是女性常见的恶性肿瘤之一。18F-氟代脱氧葡萄糖(fluorodeoxyglucose,FDG)正电子发射断层扫描/X射线计算机体层扫描(PET/CT)作为一种功能显像技术,能更有效地诊断宫颈癌病变,减少漏诊,可用于宫颈癌的早期发现、诊断及疗效和复发监测。现就其在宫颈癌诊断、治疗的最新进展,综述如下。

Cervical cancer is the common malignancies in woman. 18 F-fluorodeoxyglucose (18 F-FDG) positron emission tomography / computed tomography (PET/CT) is a well-established method for early detection, diagnosis, monitoring of therapeutic response and cancer recurrence of cervical cancer. This review focused on diagnosis and treatment of the research progress of 18F-FDG PET/CT used in cervical cancer.

1 Jemal A, Bray F, Center MM. Global cancer statistics [ J]. CA Cancer J Clin,2011,49 (1):33-64.
2 National Cancer Institute. Surveillance, epidemiology and end results (SEER) cancer statistics review, 1975-2002 [EB/OL]. (2009-01-21) [2011-03-01] http://seer.cancer.gov/csr/1975_ 2002/.
3 Wan XL, Cai Q, Zhang J, et al. Prognostic factors of cervical cancer and the difficulties and progress of primary staging [J/CD]. Chin J Obstet Gynecol Pediatr (Electron Ed), 2008, 4(6): 59-62. [万晓丽,柴青,张建,等.影响宫颈癌预后的因素及现有临床分期的难点与进展[J/CD].中华妇幼临床医学杂志:电子版,2008,4 (6):59-62.]
4 Agress H Jr, Wong TZ, Shreve P. Interpretation and reporting of positron emission tomography-computed tomographic scans [ J]. Semin Ultrasound CT MR,2008,29(4) :283-290.
5 Czernin J, Benz MR, Allen-Auerbach MS, et al. PET/CT imaging: The incremental value of assessing the glucose metabolic phenotype and the structure of cancers in a single examination[J]. Eur J Radiol,2010,73(3) :470-480.
6 Wang JQ. The performance and application of 18F-FDG PET/CT in diagnosis of tumor [J]. Foreign Med Sci: Sect Radiat Med Nuclear Med,2004, 28(2):49-53.[王俊起.18F-FDG PET/CT的特点及其在肿瘤诊断中的应用[J].国外医学:放射医学核医学分册,2004,28(2):49-53.]
7 Ng SH, Ko SF, Toh CH, et al. Imaging of neck metastases [J]. Chang Gung Med J, 2006, 29(2): 119-129.
8 Zheng H, Chen JZ, Luo RC, et al. The Value of 18F-FDG PET/ CT in the diagnosis and treatment of cervical cancer [J]. Pract J Cancer, 2009, 24(5):494-497.[郑航,陈锦章,罗荣城,等.18F FDG PET/CT显像对宫颈癌诊断及治疗的影响[J].实用癌症杂志,2009,24(5):494-497.]
9 Groheux D, Hindie E, Baillet G, et al. Advantages of PET-CT in the work-up of cervical cancer[J]. Bull Cancer, 2009, 96 (2): 199-211.
10 Loft A, Berthelsen AK, Roed H, et al. The diagnostic value of PET/CT scanning in patients with cervical cancer: A prospective study [J]. Gynecol Oncol, 2007, 106(1) : 29-34.
11 Yildirim Y, Sehirali S, Avci ME, et al. Integrated PET/CT for the evaluation of para-aortic nodal metastasis in locally advanced cervical cancer patients with negative conventional CT findings[J]. Gynecol Oncol, 2008,108(1): 154-159.
12 Qui JT, Ho KC, Lai CH, et al. Supraclavicular lymph node metastases in cervical cancer[J]. Eur J Gynaecol Oncol,2007,28(1): 33-38.
13 Husain A, Akhurst T, Larson S, et al. A prospective study of the accuracy of 18 Fluorodeoxyglucose positron emission tomography (18 FDG PET) in identifying sites of metastasis prior to pelvic exenteration[J]. Gynecol Oncol, 2007, 106 (1) : 177-180.
14 Jover R, Lourido D,Gonzalez C, et al. Role of PET/CT in the evaluation of cervical cancer [J]. Gynecol Oncol, 2008, 110 (3):S55-S59.
15 Kitajima K, Murakami K, Yamasaki E, et al. Performance of integrated FDG-PET/contrast-enhanced CT in the diagnosis of recurrent uterine cancer: Comparison with PET and enhanced CT[J]. Eur J Nucl Med Mol Imag, 2009, 36(3): 362-372.
16 Wang JH, Yang JX, Shen K, et al. The role of PET scan in the detection of recurrent cervical cancer [ J]. Prog Obstet Gynecol, 2006,15 (12) :911-913. [王瑾晖,杨佳欣,沈铿,等. PET在监测宫颈癌复发中的应用 [J].现代妇产科进展,2006,15 (12):911-913.]
17 Kitajima K, Murakami K, Yamasaki E. Performance of FDG-PET/CT for diagnosis of recurrent uterine cervical cancer[J]. Eur Radiol,2008,18(10):2040-2047.
18 Yen TC, See LC. Defining the priority of using 18 F-FDG PET for recurrent cervical cancer [J]. J Nucl Med, 2004, 45 (10): 1632-1639.
19 Jao MS, Chang TC, Chang HP, et al. Long-term follow up of cervical cancer patients with unexplained squamous cell carcinoma antigen elevation after post-therapy surveillance using positron emission tomography [J]. J Obstet Gynaecol Res, 2010, 36 (5): 1003-1008.
20 Grigsby PW. PET/CT imaging to guide cervical cancer therapy [J]. Future Oncol, 2009,5(7): 953-958.
21 Bjurberg M, Kjellén E, Ohlsson T, et al. FDG-PET in cervical cancer: Staging, restaging and follow-up[J]. Acta Obstet Gynecol Scand, 2007, 86:1384-1391.
22 Sironi S, Buda A, Picchio M, et al. Lymph node metastasis in patients with clinical early-stage cervical cancer: Detection with integrated FDG PET/CT[J]. Radiology, 2006, 238(1):272-279.
23 Yen TC, See LC, Lai CH, et al. 18F-FDG uptake in squamous cell carcinoma of the cervix is correlated with glucose transporter 1 expression[J]. J Nucl Med, 2004, 45 (10): 22-29.
24 Ong LC, Jin Y, Song IC, et al. 2-[18F]-2-deoxy-D-glucose (FDG) uptake in human tumor cells is related to the expression of GLUT-1 and hexokinase II[J]. Acta Radiol, 2008, 49(10): 1145-1153.
25 Huang JM, Pan LP, Li DX. The application of PET and PET-CT in cervical cancer [J]. Int J Radiat Med Nucl Med, 2007,31(2):112-114.[黄建敏,潘莉萍,李冬雪. PET和PET-CT在宫颈癌中的应用价值[J].国际放射医学核医学杂志,2007,31(2) :112-114.]
[1] 王亚红, 蔡胜, 葛志通, 杨筱, 李建初. 颅骨骨膜窦的超声表现一例[J/OL]. 中华医学超声杂志(电子版), 2024, 21(11): 1089-1091.
[2] 史学兵, 谢迎东, 谢霓, 徐超丽, 杨斌, 孙帼. 声辐射力弹性成像对不可切除肝细胞癌门静脉癌栓患者放射治疗效果的评价[J/OL]. 中华医学超声杂志(电子版), 2024, 21(08): 778-784.
[3] 李华志, 曹广, 刘殿刚, 张雅静. 不同入路下行肝切除术治疗原发性肝细胞癌的临床对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 52-55.
[4] 陈浩, 王萌. 胃印戒细胞癌的临床病理特征及治疗选择的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 108-111.
[5] 刘柏隆, 周祥福. 压力性尿失禁阶梯治疗的项目介绍[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 125-125.
[6] 刘柏隆. 女性压力性尿失禁阶梯治疗之手术治疗方案选择[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 126-126.
[7] 李浩, 陈棋帅, 费发珠, 张宁伟, 李元东, 王硕晨, 任宾. 慢性肝病肝纤维化无创诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(09): 863-867.
[8] 谭瑞义. 小细胞骨肉瘤诊断及治疗研究现状与进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(08): 781-784.
[9] 崔军威, 蔡华丽, 胡艺冰, 胡慧. 亚甲蓝联合金属定位夹及定位钩针标记在乳腺癌辅助化疗后评估腋窝转移淋巴结的临床应用价值探究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 625-632.
[10] 王誉英, 刘世伟, 王睿, 曾娅玲, 涂禧慧, 张蒲蓉. 老年乳腺癌新辅助治疗病理完全缓解的预测因素分析[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 641-646.
[11] 王子阳, 王宏宾, 刘晓旌. 血清标志物对甲胎蛋白阴性肝细胞癌诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 677-681.
[12] 陈慧, 邹祖鹏, 周田田, 张艺丹, 张海萍. 皮肤镜对头皮红斑性皮肤病辅助鉴别诊断的研究进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 692-698.
[13] 张平骥, 徐钰, 李天水, 庞文翼, 符师宁, 张梦圆. 重症患者镇静治疗现状及期望的调查研究[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 562-567.
[14] 胡云鹤, 周玉焯, 付瑞瑛, 于凡, 李爱东. CHS-DRG付费制度下GB1分组住院费用影响因素分析与管理策略探讨[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 568-574.
[15] 王昌前, 林婷婷, 宁雨露, 王颖杰, 谭文勇. 光免疫治疗在肿瘤领域的临床应用新进展[J/OL]. 中华临床医师杂志(电子版), 2024, 18(06): 575-583.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?