探讨卵巢幼年型粒层细胞瘤(juvenile granulose cell tumor, JGCT)的临床及病理特点和治疗策略。

采取回顾性分析法分析1996年1月至2009年12月本院收治的3例(均为女性，年龄为8个月～4岁)卵巢幼年型粒层细胞瘤患儿的临床病历资料，分析其诊治特点。

3例患儿均为右侧卵巢来源的粒层细胞瘤，临床症状以腹痛、腹胀、和腹部包块为首发。其中1例伴阴道流血及第二性征发育。对3例患儿均手术完整切除肿瘤，经病理学检查证实为幼年型粒层细胞瘤。术后，3例患儿均未行放、化疗，随访2～10年，未见肿瘤复发。

并非所有卵巢幼年型粒层细胞瘤患儿均出现假性性早熟临床表现，部分患儿也可以腹痛、腹胀和腹部包块等为首发症状，若对其能早期、完整手术切除肿瘤，则可不必行放、化疗，且预后良好。

To analyze the feature in clinic and pathology of ovarian juvenile granulose cell tumor (JGCT).

From January 1996 to December 2009, the clinical data of 3 girls at the age from 8-month to 4-year-old with ovarian juvenile granulose cell tumor which were treated at the Department of Pediatric Surgery, West China Hospital of Sichuan University were studied retrospectively.

All of 3 girls had ovarian juvenile granulose cell tumor which originated from right ovary. Abdominal pain, abdominal distention and abdominal mass were found as the first symptoms. Among them, 1 case associated with vaginal bleeding and development of secondary sexual characteristics. Complete excision of the masses was perfumed. The pathological examination revealed ovarian juvenile granulose cell tumor. These 3 cases had a good prognosis in the follow-up (2-10 years) without any adjuvant chemotherapy or radiotherapy.

Children with ovarian juvenile granulose cell tumor may not have pseudo-precocious puberty. Abdominal pain, abdominal distention, and abdominal mass could be the first manifestations. It is unnecessary for curing ovarian juvenile granulose cell tumor to be administered by adjuvant chemotherapy or radiotherapy if the tumor can be excised completely early.