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中华妇幼临床医学杂志(电子版) ›› 2010, Vol. 06 ›› Issue (05) : 371 -373. doi: 10.3877/cma.j.issn.1673-5250.2010.05.022

综述

无创性产前诊断胎儿染色体异常的研究进展
赵晓曦   
  1. 010050 呼和浩特市,内蒙古医学院第一附属医院妇产科
  • 出版日期:2010-10-01

Research Progress on Noninvasive Prenatal Diagnosis of Fetal Chromosomal Abnormalities

Xiao-xi ZHAO   

  1. Department of Obstetrics and Gynecology, First Affiliated Hospital of Inner Mongolia Medical College, Hohhot 010050, China.
  • Published:2010-10-01
引用本文:

赵晓曦. 无创性产前诊断胎儿染色体异常的研究进展[J]. 中华妇幼临床医学杂志(电子版), 2010, 06(05): 371-373.

Xiao-xi ZHAO. Research Progress on Noninvasive Prenatal Diagnosis of Fetal Chromosomal Abnormalities[J]. Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition), 2010, 06(05): 371-373.

利用孕妇外周血和宫颈黏液中胎儿来源物质,对胎儿染色体病进行诊断,一直是产前诊断领域的研究热点。本文对近年来用孕妇外周血和宫颈黏液中胎儿细胞和孕妇外周血中游离胎儿DNA/RNA,进行无创性产前监测胎儿染色体非整倍体异常的研究,综述如下。

The discovery of transcervical cells and fetal cells, cell-free fetal DNA and RNA in maternal blood has opened up new possibilities for noninvasive prenatal diagnosis. The potential application of those technologies for noninvasive prenatal detection of fetal chromosomal abnormalities is new aspects of this field that is being actively investigated. This article gives a review of the current state of the study.

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