分析不明原因不孕患者小卵泡排卵(ovulated with small follicle，OSF)的临床特征。

用回顾性方法分析46例不明原因不孕患者。本组经临床诊断为OSF的不孕症患者25例为OSF组，其余21例为对照组。

本组不明原因不孕妇女中，OSF患者所占的构成比为54. 35%(25/46)。OSF患者中，64%(16/25)患者有自然流产史，明显高于对照组。对OSF患者中的20例进行了2个周期以上的监测，其重复出现率为85% (17/20)，表现为黄体功能不足(luteal phase defect，LPD)的患者占52%(13/25)。

OSF重复出现率高，是引起不孕的主要原因之一。该病患者以前多被诊断为LPD或不明原因不孕。经阴道超声联合尿LH试纸测定监测排卵，是诊断OSF的主要方法。因OSF导致的自然流产率高，故建议OSF周期取消治疗计划。

To investigate the clinical features of infertile women ovulated with small follicle (OSF).

Transvaginal B-ultrasonography was used for infertile women to monitor the follicular development during nature cycles, then the date of clinical features of OSF were analyzed retrospectively.

Among 46 unexplained infertile women, there were 25 (54. 35%) with OSF. Among OSF case, 64% had history of spontaneous abortion, 52% showed luteal phase defect (LPD).

OSF might be a cause infertility. Patients often had been diagnosed as LPD or unexplained infertility and had spontaneous abortion history. Transvaginal ultrosonography with urine LH test paper is a major diagnostic method. Since there is higher rate of spontaneous abortion, it is suggested to cancel the treatment cycle when OSF has been found.